Tadalista 20 is a medication used to treat erectile dysfunction (ED). It contains tadalafil, which is the same active ingredient found in Cialis. Tadalafil, the active ingredient in Tadalista 20 for Sale, is a phosphodiesterase type 5 (PDE5) inhibitor. PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a molecule that helps relax smooth muscles in the blood vessels of the penis. By inhibiting PDE5, tadalafil increases the levels of cGMP, leading to the relaxation of these muscles and improved blood flow to the penis.