Psychiatric conditions or mental health disorders typically don't directly affect the duration of effectiveness of Penegra 100 mg, which contains Sildenafil citrate. However, certain psychological factors may indirectly influence its effectiveness:

Stress and Anxiety: High levels of stress and anxiety can interfere with sexual arousal and performance. They may make it more challenging to achieve and maintain an erection, potentially shortening the duration of Penegra's effectiveness.

Depression: Depression can reduce libido and interest in sexual activity, affecting the overall effectiveness of Penegra. Additionally, antidepressant medications used to treat depression can sometimes cause sexual side effects, which may impact the response to Penegra.

Psychological Trauma: Past psychological trauma or negative sexual experiences can lead to performance anxiety or fear of intimacy, which can affect the effectiveness of Penegra.

Body Image Issues: Body image concerns or low self-esteem can contribute to sexual insecurities, affecting the ability to achieve and maintain an erection, and potentially impacting the duration of penegra 100 effectiveness.

Relationship Problems: Issues within a relationship, such as communication problems, unresolved conflicts, or lack of emotional intimacy, can affect sexual performance and the effectiveness of Penegra.

While these psychological factors may not directly influence the pharmacological action of Penegra, they can impact sexual function and overall satisfaction with treatment. It's essential for individuals experiencing such issues to seek support from mental health professionals or counselors who can address these concerns alongside medical treatment for erectile dysfunction.